Kidney Stone Research

Usefulness of Hounsfield Unit & Density in the Assessment & Treatment of Urinary Stones

Usefulness of Hounsfield Unit & Density in the Assessment & Treatment of Urinary Stones

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Hounsfield units provide information not only for the diagnosis of urinary system tumors but also regarding a number of properties of urinary stones. Computed tomography is currently used most commonly to predict the type of stone and assess the potential efficacy of extracorporeal shock wave lithotripsy treatment. However, it might also assist urologists to decide which of percutaneous nephrolithotomy, ureterorenoscopic ureterolithotripsy, and medical expulsive treatment should be used to treat a patient.
Distribution of Ureteral Stones & Factors Affecting Their Location & Expulsion in Patient with Renal Colic

Distribution of Ureteral Stones & Factors Affecting Their Location & Expulsion in Patient with Renal Colic

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The upper ureter and ureterovesical junction (UVJ) were 2 peak locations at which stones initially lodged. Stones lodged at the upper ureter and ureteropelvic junction (group A) had a larger longitudinal diameter (4.21 mm vs. 3.56 mm, p=0.004) compared to those lodged at the lower ureter and UVJ (group B). The expulsion rate was 75.6% and 94.9% in groups A and B, respectively. There was no significant difference in the time interval from initiation of renal colic to arrival at the ED between groups A and B (p=0.422).
NSAID Effects On Kidney Function

NSAID Effects On Kidney Function

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Nonsteroidal anti-inflammatory drugs (NSAIDs) are capable of inducing a variety of renal function abnormalities, particularly in high-risk patients with decreased renal blood perfusion who depend on prostaglandin synthesis to maintain normal renal function. Fluid retention is the most common NSAID-related renal complication, occurring to some degree in virtually all exposed individuals; however, clinically detectable edema occurs in less than 5% of patients and is readily reversible on discontinuation of the NSAID.
Significant Acute Kidney Injury Due to Non Steroidal Anti-Inflammatory Drugs

Significant Acute Kidney Injury Due to Non Steroidal Anti-Inflammatory Drugs

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In the United States non-steroidal anti-inflammatory drugs (NSAID) are freely available over-the-counter. Because of the adverse effects on the kidneys and the popularity of these drugs, unregulated use of NSAIDs is an under recognized and potentially dangerous problem.

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